C Arnold Spek Selected Research

C Arnold Spek Research Topics

Disease

36	Neoplasms (Cancer) 02/2022 - 01/2004
19	Inflammation (Inflammations) 01/2022 - 01/2003
12	Fibrosis (Cirrhosis) 01/2021 - 02/2008
12	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2004
10	Pulmonary Fibrosis (Fibrosing Alveolitis) 06/2022 - 12/2010
10	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022 - 07/2010
9	Sepsis (Septicemia) 09/2007 - 01/2003
8	Infections 11/2016 - 08/2006
7	Adenocarcinoma 01/2022 - 07/2010
7	Disease Progression 04/2020 - 10/2008
6	Diabetic Nephropathies (Diabetic Nephropathy) 10/2019 - 01/2016
5	Idiopathic Pulmonary Fibrosis 07/2018 - 12/2010
5	Disseminated Intravascular Coagulation 11/2007 - 01/2003
4	Pneumonia (Pneumonitis) 01/2022 - 10/2005
4	Bacterial Infections (Bacterial Infection) 05/2015 - 02/2010
4	Shwartzman Phenomenon (Shwartzman Reaction) 11/2007 - 01/2003
4	Thrombosis (Thrombus) 10/2007 - 11/2003
4	Endotoxemia 12/2006 - 01/2003
3	Lung Diseases (Lung Disease) 01/2022 - 06/2015
3	Pneumococcal Pneumonia 11/2018 - 06/2006
3	Hemorrhage 03/2017 - 01/2008
3	Colonic Neoplasms (Colon Cancer) 06/2010 - 01/2009
3	Cardiovascular Diseases (Cardiovascular Disease) 04/2010 - 03/2005
2	Acute Lung Injury 01/2022 - 04/2013
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2019 - 01/2017
2	Hyperglycemia 04/2018 - 10/2007
2	Venous Thrombosis (Deep-Vein Thrombosis) 08/2015 - 08/2006
2	Lymphatic Metastasis 05/2015 - 11/2014
2	Ischemia 01/2013 - 09/2007
2	Melanoma (Melanoma, Malignant) 01/2013 - 01/2009
2	Atherosclerotic Plaque (Atheroma) 09/2012 - 10/2006
2	Breast Neoplasms (Breast Cancer) 09/2012 - 06/2010
2	Colitis 09/2011 - 09/2007
2	Myocardial Infarction 04/2010 - 03/2005
2	Fever (Fevers) 02/2010 - 02/2010
2	Reperfusion Injury 07/2009 - 09/2007
2	Myocardial Ischemia (Ischemic Heart Diseases) 07/2009 - 08/2008
2	Osteosarcoma (Osteogenic Sarcoma) 05/2009 - 12/2003
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2009 - 09/2007
2	Vascular System Injuries 01/2008 - 01/2003
2	Carotid Artery Thrombosis 10/2007 - 11/2003
2	Peritonitis 08/2006 - 06/2004
2	Necrosis 08/2006 - 06/2005
2	Multiple Organ Failure (MODS) 06/2005 - 01/2003

Drug/Important Bio-Agent (IBA)

19	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 11/2007
14	Thromboplastin (Tissue Factor)IBA 11/2018 - 11/2003
13	Proteinase-Activated ReceptorsIBA 12/2020 - 01/2008
13	Thrombin FDA Link 10/2020 - 06/2004
11	AnticoagulantsIBA 10/2020 - 06/2004
10	Bleomycin (Blenoxane)FDA LinkGeneric 06/2022 - 12/2010
10	Protein CIBA 01/2016 - 08/2006
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2004
9	Transcription Factors (Transcription Factor)IBA 01/2021 - 07/2006
8	Blood Coagulation Factors (Coagulation Factor)IBA 08/2015 - 01/2005
7	PAR-2 ReceptorIBA 11/2018 - 03/2010
6	CCAAT-Enhancer-Binding Protein-deltaIBA 01/2021 - 12/2012
6	CCAAT-Enhancer-Binding ProteinsIBA 09/2020 - 09/2007
6	CytokinesIBA 01/2019 - 06/2003
6	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 08/2015 - 06/2005
6	FibrinIBA 09/2011 - 06/2004
5	Hydroxyproline (4 Hydroxyproline)IBA 01/2021 - 02/2014
5	Factor VIIa (Activated Factor VII)IBA 11/2018 - 01/2004
5	Factor Xa (Coagulation Factor Xa)IBA 06/2010 - 07/2007
5	EndotoxinsIBA 03/2010 - 03/2004
5	Dacarbazine (DIC)FDA LinkGeneric 11/2007 - 01/2003
4	Messenger RNA (mRNA)IBA 12/2019 - 03/2005
4	Streptozocin (Streptozotocin)FDA Link 04/2018 - 10/2007
4	C-Reactive ProteinIBA 04/2010 - 03/2005
3	Gemcitabine FDA Link 01/2022 - 03/2017
3	Pharmaceutical PreparationsIBA 07/2021 - 08/2006
3	Biomarkers (Surrogate Marker)IBA 04/2020 - 03/2005
3	CollagenIBA 07/2018 - 10/2007
3	AntithrombinsIBA 03/2017 - 06/2004
3	LigandsIBA 09/2012 - 01/2009
3	factor V LeidenIBA 12/2008 - 08/2006
3	Interleukin-6 (Interleukin 6)IBA 10/2007 - 08/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2007 - 08/2006
2	DNA (Deoxyribonucleic Acid)IBA 06/2022 - 01/2021
2	Silicon Dioxide (Silica)FDA LinkGeneric 02/2022 - 07/2021
2	platelet activating factor receptorIBA 01/2021 - 06/2012
2	Metalloproteases (Metalloproteinases)IBA 04/2020 - 01/2013
2	Blood Glucose (Blood Sugar)IBA 10/2019 - 10/2007
2	vorapaxarIBA 10/2019 - 04/2018
2	Fibronectins (Fibronectin)IBA 07/2018 - 04/2018
2	ThrombomodulinIBA 09/2011 - 11/2003
2	cyclopamineIBA 07/2010 - 08/2008
2	Factor X (Stuart Factor)IBA 06/2010 - 06/2009
2	Fibrinogen (Factor I)FDA Link 04/2010 - 01/2009
2	Factor VIII (Coagulation Factor VIII)IBA 04/2010 - 12/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2010 - 05/2009
2	HirudinsIBA 06/2009 - 01/2009
2	ferric chlorideIBA 10/2007 - 11/2003
2	CreatinineIBA 09/2007 - 06/2005
2	antithrombin III-protease complexIBA 08/2006 - 06/2006
1	Interleukin-4 (Interleukin 4)IBA 06/2022
1	MethyltransferasesIBA 06/2022
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2022
1	Fluorouracil (Carac)FDA LinkGeneric 01/2022

Therapy/Procedure

8	Therapeutics 10/2020 - 07/2009
2	Drug Therapy (Chemotherapy) 02/2022 - 01/2022